B7-H1 Promotes Germinal Center B cell Survival and Inhibits T cell Activation

The immune system has developed several regulatory mechanisms to maintain homeostasis of adaptive immune responses. T cell PD-1 recognition of B7-H1 (PD-L1) expressed on antigen presenting cells and non-lymphoid tissue regulates T cell activation. We show that B7-H1(−/−) mice exhibit exacerbated pro...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Hamel, Keith M., Cao, Yanxia, Wang, Yumei, Rodeghero, Rachel, Kobezda, Tamas, Chen, Lieping, Finnegan, Alison
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638795/
https://ncbi.nlm.nih.gov/pubmed/21061440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040690
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk