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Location of CD4(+) T cell Priming Regulates the Differentiation of Th1 and Th17 cells and their Contribution to Arthritis
T helper (Th) cytokines IFN-γ and IL-17 are linked to the development of autoimmune disease. In models of rheumatoid arthritis (RA) i.e. proteoglycan (PG) -induced arthritis (PGIA), IFN-γ is required whereas in collagen-induced arthritis, IL-17 is necessary for development of arthritis. Here we show...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690552/ https://ncbi.nlm.nih.gov/pubmed/23630349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203045 |
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