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Small self-RNA generated by RNase L amplifies antiviral innate immunity
Antiviral innate immunity is initiated in response to RNA molecules that are produced in virus-infected cells(1). These RNAs activate signalling cascades that activate the genes that encode α- and β-interferon (IFN). Signalling occurs through the interaction of the RNAs with either of two pathogen r...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638316/ https://ncbi.nlm.nih.gov/pubmed/17653195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06042 |
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