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RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP
Triggering and propagating an intracellular innate immune response is essential for control of viral infections. RNase L is a host endoribonuclease and a pivotal component of innate immunity that cleaves viral and cellular RNA within single-stranded loops releasing small structured RNAs with 5′-hydr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957051/ https://ncbi.nlm.nih.gov/pubmed/20833746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2244210 |
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