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On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme
Transcription in eukaryotes produces a number of long noncoding RNAs (lncRNAs). Two of these, MALAT1 and Menβ, generate a tRNA-like small RNA in addition to the mature lncRNA. The stability of these tRNA-like small RNAs and bona fide tRNAs is monitored by the CCA-adding enzyme. Whereas CCA is added...
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| Publicado no: | Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329729/ https://ncbi.nlm.nih.gov/pubmed/25640237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.005 |
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