Targeted Therapy for BRAF(V600E) Malignant Astrocytoma

PURPOSE: Malignant astrocytomas (MAs) are aggressive central nervous system tumors with poor prognosis. Activating mutation of BRAF (BRAF(V600E)) has been reported in a subset of these tumors, especially in children. We have investigated the incidence of BRAF(V600E) in additional pediatric patient c...

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Detalhes bibliográficos
Main Authors: Nicolaides, Theodore P., Li, Huifang, Solomon, David A., Hariono, Sujatmi, Hashizume, Rintaro, Barkovich, Krister, Baker, Suzanne J., Paugh, Barbara S., Jones, Chris, Forshew, Tim, Hindley, Guy F., Hodgson, J. Graeme, Kim, Jung-Sik, Rowitch, David H., Weiss, William A., Waldman, Todd A., James, C. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638050/
https://ncbi.nlm.nih.gov/pubmed/22038996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1456
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