SURVIVAL ADVANTAGE COMBINING A BRAF INHIBITOR AND RADIATION IN BRAF V600E-MUTANT GLIOMA

PURPOSE: Radiation (RT) is critical to the treatment of high-grade gliomas (HGGs) but cures remain elusive. The BRAF mutation V600E is critical to the pathogenesis of 10–20% of pediatric gliomas, and a small proportion of adult HGGs. Here we aim to determine whether PLX4720, a specific BRAF V600E in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Dasgupta, Tina, Olow, Aleksandra K., Yang, Xiaodong, Hashizume, Rintaro, Tom, Maxwell, Aoki, Yasuyuki, Berger, Mitchel S., Weiss, William A., Stalpers, Lukas J. A., Prados, Michael, James, C. David, Mueller, Sabine, Haas-Kogan, Daphne A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907264/
https://ncbi.nlm.nih.gov/pubmed/26384810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-015-1939-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados