Targeted Therapy for BRAF(V600E) Malignant Astrocytoma

PURPOSE: Malignant astrocytomas (MAs) are aggressive central nervous system tumors with poor prognosis. Activating mutation of BRAF (BRAF(V600E)) has been reported in a subset of these tumors, especially in children. We have investigated the incidence of BRAF(V600E) in additional pediatric patient c...

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主要な著者: Nicolaides, Theodore P., Li, Huifang, Solomon, David A., Hariono, Sujatmi, Hashizume, Rintaro, Barkovich, Krister, Baker, Suzanne J., Paugh, Barbara S., Jones, Chris, Forshew, Tim, Hindley, Guy F., Hodgson, J. Graeme, Kim, Jung-Sik, Rowitch, David H., Weiss, William A., Waldman, Todd A., James, C. David
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638050/
https://ncbi.nlm.nih.gov/pubmed/22038996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1456
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