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Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1

Th17 cells are highly proinflammatory cells critical for clearing extracellular pathogens and for induction of multiple autoimmune diseases(1). IL-23 plays a critical role in stabilizing and reinforcing the Th17 phenotype by increasing expression of IL-23 receptor (IL-23R) and endowing Th17 cells wi...

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Detalhes bibliográficos
Main Authors: Wu, Chuan, Yosef, Nir, Thalhamer, Theresa, Zhu, Chen, Xiao, Sheng, Kishi, Yasuhiro, Regev, Aviv, Kuchroo, Vijay
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637879/
https://ncbi.nlm.nih.gov/pubmed/23467085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11984
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