Induction and molecular signature of pathogenic T(H)17 cells

Interleukin 17 (IL-17)-producing T(H)17 cells are often present at the sites of tissue inflammation in autoimmune diseases, which has lead to the conclusion that T(H)17 are main drivers of autoimmune tissue injury. However, not all T(H)17 cells are pathogenic, in fact T(H)17 generated with TGF-β1 an...

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Hlavní autoři: Lee, Youjin, Awasthi, Amit, Yosef, Nir, Quintana, Francisco J., Xiao, Sheng, Peters, Anneli, Wu, Chuan, Kleinewietfeld, Markus, Kunder, Sharon, Hafler, David, Sobel, Raymond A., Regev, Aviv, Kuchroo, Vijay K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459594/
https://ncbi.nlm.nih.gov/pubmed/22961052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2416
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