Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases

BACKGROUND: Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. We have recently demonstrated that B. abortus infects microglia and astrocytes, eliciting the production of a variety of pro-inflammatory cytokines which c...

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Hauptverfasser: Miraglia, M Cruz, Scian, Romina, Samartino, Clara García, Barrionuevo, Paula, Rodriguez, Ana M, Ibañez, Andrés E, Coria, Lorena M, Velásquez, Lis N, Baldi, Pablo C, Cassataro, Juliana, Delpino, M Victoria, Giambartolomei, Guillermo H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637408/
https://ncbi.nlm.nih.gov/pubmed/23587438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-47
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