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Granulocyte-Macrophage Colony-Stimulating Factor- and Tumor Necrosis Factor Alpha-Mediated Matrix Metalloproteinase Production by Human Osteoblasts and Monocytes after Infection with Brucella abortus

Osteoarticular complications are common in human brucellosis, but the pathogenic mechanisms involved are largely unknown. Since matrix metalloproteinases (MMPs) are involved in joint and bone damage in inflammatory and infectious diseases, we investigated the production of MMPs by human osteoblasts...

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Autores principales: Scian, Romina, Barrionuevo, Paula, Giambartolomei, Guillermo H., Fossati, Carlos A., Baldi, Pablo C., Delpino, M. Victoria
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019911/
https://ncbi.nlm.nih.gov/pubmed/20956574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00934-10
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