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Granulocyte-Macrophage Colony-Stimulating Factor- and Tumor Necrosis Factor Alpha-Mediated Matrix Metalloproteinase Production by Human Osteoblasts and Monocytes after Infection with Brucella abortus

Osteoarticular complications are common in human brucellosis, but the pathogenic mechanisms involved are largely unknown. Since matrix metalloproteinases (MMPs) are involved in joint and bone damage in inflammatory and infectious diseases, we investigated the production of MMPs by human osteoblasts...

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Detalhes bibliográficos
Main Authors: Scian, Romina, Barrionuevo, Paula, Giambartolomei, Guillermo H., Fossati, Carlos A., Baldi, Pablo C., Delpino, M. Victoria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019911/
https://ncbi.nlm.nih.gov/pubmed/20956574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00934-10
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