Potential Role of Fibroblast-Like Synoviocytes in Joint Damage Induced by Brucella abortus Infection through Production and Induction of Matrix Metalloproteinases

Arthritis is one of the most common complications of human brucellosis, but its pathogenic mechanisms have not been elucidated. Fibroblast-like synoviocytes (FLS) are known to be central mediators of joint damage in inflammatory arthritides through the production of matrix metalloproteinases (MMPs)...

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Main Authors: Scian, Romina, Barrionuevo, Paula, Giambartolomei, Guillermo H., De Simone, Emilio A., Vanzulli, Silvia I., Fossati, Carlos A., Baldi, Pablo C., Delpino, M. Victoria
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165475/
https://ncbi.nlm.nih.gov/pubmed/21730088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05408-11
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