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Potential Role of Fibroblast-Like Synoviocytes in Joint Damage Induced by Brucella abortus Infection through Production and Induction of Matrix Metalloproteinases

Arthritis is one of the most common complications of human brucellosis, but its pathogenic mechanisms have not been elucidated. Fibroblast-like synoviocytes (FLS) are known to be central mediators of joint damage in inflammatory arthritides through the production of matrix metalloproteinases (MMPs)...

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Detalhes bibliográficos
Main Authors: Scian, Romina, Barrionuevo, Paula, Giambartolomei, Guillermo H., De Simone, Emilio A., Vanzulli, Silvia I., Fossati, Carlos A., Baldi, Pablo C., Delpino, M. Victoria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165475/
https://ncbi.nlm.nih.gov/pubmed/21730088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05408-11
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