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Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases

BACKGROUND: Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. We have recently demonstrated that B. abortus infects microglia and astrocytes, eliciting the production of a variety of pro-inflammatory cytokines which c...

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Detalhes bibliográficos
Main Authors: Miraglia, M Cruz, Scian, Romina, Samartino, Clara García, Barrionuevo, Paula, Rodriguez, Ana M, Ibañez, Andrés E, Coria, Lorena M, Velásquez, Lis N, Baldi, Pablo C, Cassataro, Juliana, Delpino, M Victoria, Giambartolomei, Guillermo H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637408/
https://ncbi.nlm.nih.gov/pubmed/23587438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-47
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