Defective Lung Macrophage Function in Lung Cancer±Chronic Obstructive Pulmonary Disease (COPD/Emphysema)-Mediated by Cancer Cell Production of PGE2?

In chronic obstructive pulmonary disease (COPD/emphysema) we have shown a reduced ability of lung and alveolar (AM) macrophages to phagocytose apoptotic cells (defective ‘efferocytosis’), associated with evidence of secondary cellular necrosis and a resultant inflammatory response in the airway. It...

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Main Authors: Dehle, Francis C., Mukaro, Violet R., Jurisevic, Craig, Moffat, David, Ahern, Jessica, Hodge, Greg, Jersmann, Hubertus, Reynolds, Paul N., Hodge, Sandra
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637201/
https://ncbi.nlm.nih.gov/pubmed/23637858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061573
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