The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation

The adaptor molecule signaling lymphocytic activation molecule–associated protein (SAP) plays critical roles during invariant natural killer T (iNKT) cell ontogeny. As a result, SAP-deficient humans and mice lack iNKT cells. The strict developmental requirement for SAP has made it difficult to disce...

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Bibliographische Detailangaben
Hauptverfasser: Das, Rupali, Bassiri, Hamid, Guan, Peng, Wiener, Susan, Banerjee, Pinaki P., Zhong, Ming-Chao, Veillette, André, Orange, Jordan S., Nichols, Kim E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637014/
https://ncbi.nlm.nih.gov/pubmed/23430111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-468868
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