The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation

The adaptor molecule signaling lymphocytic activation molecule–associated protein (SAP) plays critical roles during invariant natural killer T (iNKT) cell ontogeny. As a result, SAP-deficient humans and mice lack iNKT cells. The strict developmental requirement for SAP has made it difficult to disce...

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Detalhes bibliográficos
Main Authors: Das, Rupali, Bassiri, Hamid, Guan, Peng, Wiener, Susan, Banerjee, Pinaki P., Zhong, Ming-Chao, Veillette, André, Orange, Jordan S., Nichols, Kim E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637014/
https://ncbi.nlm.nih.gov/pubmed/23430111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-468868
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