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Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn

SAP is an adaptor protein that is expressed in NK and T cells. It is mutated in humans who have X-linked lymphoproliferative (XLP) disease. By interacting with SLAM family receptors, SAP enables tyrosine phosphorylation signaling of these receptors by its ability to recruit the Src-related kinase, F...

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Detalhes bibliográficos
Main Authors: Bloch-Queyrat, Coralie, Fondanèche, Marie-Claude, Chen, Riyan, Yin, Luo, Relouzat, Francis, Veillette, André, Fischer, Alain, Latour, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212903/
https://ncbi.nlm.nih.gov/pubmed/15998796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050449
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