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Association between SAP and FynT: Inducible SH3 Domain-Mediated Interaction Controlled by Engagement of the SLAM Receptor

SAP is an intracellular adaptor molecule composed almost exclusively of an SH2 domain. It is mutated in patients with X-linked lymphoproliferative disease, a human immunodeficiency. Several immune abnormalities were also identified in SAP-deficient mice. By way of its SH2 domain, SAP interacts with...

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書誌詳細
主要な著者: Chen, Riyan, Latour, Sylvain, Shi, Xiaochu, Veillette, André
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592776/
https://ncbi.nlm.nih.gov/pubmed/16847311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00357-06
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