Multiple splicing factors are released from endogenous complexes during in vitro pre-mRNA splicing.

Pre-mRNA splicing occurs in a macromolecular complex called the spliceosome. Efforts to isolate spliceosomes from in vitro splicing reactions have been hampered by the presence of endogenous complexes that copurify with de novo spliceosomes formed on added pre-mRNA. We have found that removal of the...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Conway, G C, Krainer, A R, Spector, D L, Roberts, R J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2531283/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.12.5273-5280.1989
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