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Multiple splicing factors are released from endogenous complexes during in vitro pre-mRNA splicing.

Pre-mRNA splicing occurs in a macromolecular complex called the spliceosome. Efforts to isolate spliceosomes from in vitro splicing reactions have been hampered by the presence of endogenous complexes that copurify with de novo spliceosomes formed on added pre-mRNA. We have found that removal of the...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Conway, G C, Krainer, A R, Spector, D L, Roberts, R J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC363691/
https://ncbi.nlm.nih.gov/pubmed/2531283
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