Identification of proteins that bind tightly to pre-mRNA during in vitro splicing.
Incubation of a human beta-globin pre-mRNA in a HeLa cell nuclear extract under conditions permissive for efficient splicing resulted in the assembly of the RNA into ribonucleoprotein (RNP) complexes. This RNP formation occurred largely within the characteristic lag period that precedes splicing. Tw...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1986
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3459150/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3718 |
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