Mechanism for cryptic splice site activation during pre-mRNA splicing.
The 5' splice site of a pre-mRNA is recognized by U1 small nuclear ribonucleoprotein particles (snRNP) through base pairing with the 5' end of U1 small nuclear RNA (snRNA). Single-base substitutions within a 9-nucleotide 5'-splice-site sequence can abolish or attenuate use of that site and, in highe...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2143583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6253 |
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