Mechanism for cryptic splice site activation during pre-mRNA splicing.

The 5' splice site of a pre-mRNA is recognized by U1 small nuclear ribonucleoprotein particles (snRNP) through base pairing with the 5' end of U1 small nuclear RNA (snRNA). Single-base substitutions within a 9-nucleotide 5'-splice-site sequence can abolish or attenuate use of that site and, in highe...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Nelson, K K, Green, M R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2143583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6253
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