Real-time Kinetics of High-mobility Group Box 1 (HMGB1) Oxidation in Extracellular Fluids Studied by in Situ Protein NMR Spectroscopy

Some extracellular proteins are initially secreted in reduced forms via a non-canonical pathway bypassing the endoplasmic reticulum and become oxidized in the extracellular space. One such protein is HMGB1 (high-mobility group box 1). Extracellular HMGB1 has different redox states that play distinct...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zandarashvili, Levani, Sahu, Debashish, Lee, Kwanbok, Lee, Yong Sun, Singh, Pomila, Rajarathnam, Krishna, Iwahara, Junji
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2013
الموضوعات:
Molecular Biophysics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636853/
https://ncbi.nlm.nih.gov/pubmed/23447529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.449942
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