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NMR-based investigations into target DNA search processes of proteins

To perform their function, transcription factors and DNA-repair/modifying enzymes must first locate their targets in the vast presence of nonspecific, but structurally similar sites on genomic DNA. Before reaching their targets, these proteins stochastically scan DNA and dynamically move from one si...

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Bibliografische gegevens
Gepubliceerd in:Methods
Hoofdauteurs: Iwahara, Junji, Zandarashvili, Levani, Kemme, Catherine A., Esadze, Alexandre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133758/
https://ncbi.nlm.nih.gov/pubmed/29753002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.05.004
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