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NMR-based investigations into target DNA search processes of proteins

To perform their function, transcription factors and DNA-repair/modifying enzymes must first locate their targets in the vast presence of nonspecific, but structurally similar sites on genomic DNA. Before reaching their targets, these proteins stochastically scan DNA and dynamically move from one si...

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Detalles Bibliográficos
Publicado en:Methods
Main Authors: Iwahara, Junji, Zandarashvili, Levani, Kemme, Catherine A., Esadze, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133758/
https://ncbi.nlm.nih.gov/pubmed/29753002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.05.004
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