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NMR-based investigations into target DNA search processes of proteins

To perform their function, transcription factors and DNA-repair/modifying enzymes must first locate their targets in the vast presence of nonspecific, but structurally similar sites on genomic DNA. Before reaching their targets, these proteins stochastically scan DNA and dynamically move from one si...

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Vydáno v:Methods
Hlavní autoři: Iwahara, Junji, Zandarashvili, Levani, Kemme, Catherine A., Esadze, Alexandre
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133758/
https://ncbi.nlm.nih.gov/pubmed/29753002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.05.004
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