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NMR-based investigations into target DNA search processes of proteins

To perform their function, transcription factors and DNA-repair/modifying enzymes must first locate their targets in the vast presence of nonspecific, but structurally similar sites on genomic DNA. Before reaching their targets, these proteins stochastically scan DNA and dynamically move from one si...

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Bibliografiske detaljer
Udgivet i:Methods
Main Authors: Iwahara, Junji, Zandarashvili, Levani, Kemme, Catherine A., Esadze, Alexandre
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133758/
https://ncbi.nlm.nih.gov/pubmed/29753002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.05.004
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