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NMR-based investigations into target DNA search processes of proteins
To perform their function, transcription factors and DNA-repair/modifying enzymes must first locate their targets in the vast presence of nonspecific, but structurally similar sites on genomic DNA. Before reaching their targets, these proteins stochastically scan DNA and dynamically move from one si...
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| Veröffentlicht in: | Methods |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6133758/ https://ncbi.nlm.nih.gov/pubmed/29753002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.05.004 |
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