BDNF Action in the Brain Attenuates Diabetic Hyperglycemia via Insulin-Independent Inhibition of Hepatic Glucose Production

Recent evidence suggests that central leptin administration fully normalizes hyperglycemia in a rodent model of uncontrolled insulin-deficient diabetes by reducing hepatic glucose production (HGP) and by increasing glucose uptake. The current studies were undertaken to determine whether brain-derive...

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Autors principals: Meek, Thomas H., Wisse, Brent E., Thaler, Joshua P., Guyenet, Stephan J., Matsen, Miles E., Fischer, Jonathan D., Taborsky, Gerald J., Schwartz, Michael W., Morton, Gregory J.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2013
Matèries:
Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636618/
https://ncbi.nlm.nih.gov/pubmed/23274899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0837
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