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Survivin expression increases during aging and enhances the resistance of aged human fibroblasts to genotoxic stress
Survivin, an important anti-apoptotic protein, is highly expressed in most cancers, which generally arise in cells of older individuals. We have shown here accumulation of survivin and phospho-survivin in aged normal human skin fibroblasts and mice organs. This age-related accumulation of survivin w...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Netherlands
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3636406/ https://ncbi.nlm.nih.gov/pubmed/22252435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9378-2 |
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