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Survivin expression increases during aging and enhances the resistance of aged human fibroblasts to genotoxic stress

Survivin, an important anti-apoptotic protein, is highly expressed in most cancers, which generally arise in cells of older individuals. We have shown here accumulation of survivin and phospho-survivin in aged normal human skin fibroblasts and mice organs. This age-related accumulation of survivin w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Al-Khalaf, Huda H., Aboussekhra, Abdelilah
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Netherlands 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636406/
https://ncbi.nlm.nih.gov/pubmed/22252435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9378-2
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