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Increased expression of endoplasmic reticulum stress genes in patients with limited cutaneous Systemic Sclerosis and Pulmonary Arterial Hypertension

OBJECTIVE: Pulmonary arterial hypertension (PAH), a common complication of limited cutaneous systemic sclerosis (lcSSc), is associated with alterations of markers of inflammation and vascular damage in peripheral blood mononuclear cells (PBMCs). Endoplasmic reticulum (ER) stress and unfolded protein...

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Detalhes bibliográficos
Main Authors: Lenna, Stefania, Farina, Alessandra G., Martyanov, Viktor, Christmann, Romy B., Wood, Tammara A, Farber, Harrison W, Scorza, Raffaella, Whitfield, Michael L., Lafyatis, Robert, Trojanowska, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636187/
https://ncbi.nlm.nih.gov/pubmed/23400395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37891
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