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Calcium sensitivity and myofilament lattice structure in titin N2B KO mice

The cellular basis of the Frank-Starling “Law of the Heart” is the length-dependence of activation, but the mechanisms by which the sarcomere detects length changes and converts this information to altered calcium sensitivity has remained elusive. Here the effect of titin-based passive tension on th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lee, Eun-Jeong, Nedrud, Joshua, Schemmel, Peter, Gotthardt, Michael, Irving, Thomas C., Granzier, Henk L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636180/
https://ncbi.nlm.nih.gov/pubmed/23246787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.12.004
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