Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ

We recently showed that bitter melon-derived triterpenoids (BMTs) activate AMPK and increase GLUT4 translocation to the plasma membrane in vitro, and improve glucose disposal in insulin resistant models in vivo. Here we interrogated the mechanism by which these novel compounds activate AMPK, a leadi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Iseli, Tristan J., Turner, Nigel, Zeng, Xiao-Yi, Cooney, Gregory J., Kraegen, Edward W., Yao, Sheng, Ye, Yang, James, David E., Ye, Ji-Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636144/
https://ncbi.nlm.nih.gov/pubmed/23638033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062309
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