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Propofol inhibited autophagy through Ca(2+)/CaMKKβ/AMPK/mTOR pathway in OGD/R-induced neuron injury
BACKGROUND: The neuroprotective role of propofol (PPF) in cerebral ischemia-reperfusion (I/R) has recently been highlighted. This study aimed to explore whether the neuroprotective mechanisms of PPF were linked to its regulation of Ca(2+)/CaMKKβ (calmodulin-dependent protein kinase kinase β)/AMPK (A...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Med |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251140/ https://ncbi.nlm.nih.gov/pubmed/30470173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0054-1 |
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