Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ

We recently showed that bitter melon-derived triterpenoids (BMTs) activate AMPK and increase GLUT4 translocation to the plasma membrane in vitro, and improve glucose disposal in insulin resistant models in vivo. Here we interrogated the mechanism by which these novel compounds activate AMPK, a leadi...

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Bibliografiska uppgifter
Huvudupphovsmän: Iseli, Tristan J., Turner, Nigel, Zeng, Xiao-Yi, Cooney, Gregory J., Kraegen, Edward W., Yao, Sheng, Ye, Yang, James, David E., Ye, Ji-Ming
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636144/
https://ncbi.nlm.nih.gov/pubmed/23638033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062309
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