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Human Germline Antibody Gene Segments Encode Polyspecific Antibodies
Structural flexibility in germline gene-encoded antibodies allows promiscuous binding to diverse antigens. The binding affinity and specificity for a particular epitope typically increase as antibody genes acquire somatic mutations in antigen-stimulated B cells. In this work, we investigated whether...
Tallennettuna:
| Päätekijät: | , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3636087/ https://ncbi.nlm.nih.gov/pubmed/23637590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003045 |
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