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Mutations in the RB1 gene and their effects on transcription.

Inactivation of both alleles of the RB1 gene during normal retinal development initiates the formation of a retinoblastoma (RB) tumor. To identify the mutations which inactivate RB1, 21 RB tumors isolated from 19 patients were analyzed with the polymerase chain reaction or an RNase protection assay...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Dunn, J M, Phillips, R A, Zhu, X, Becker, A, Gallie, B L
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363605/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2601691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.11.4596
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