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Mutations in the RB1 gene and their effects on transcription.
Inactivation of both alleles of the RB1 gene during normal retinal development initiates the formation of a retinoblastoma (RB) tumor. To identify the mutations which inactivate RB1, 21 RB tumors isolated from 19 patients were analyzed with the polymerase chain reaction or an RNase protection assay...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2601691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.11.4596 |
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