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Mutations in the RB1 gene and their effects on transcription.

Inactivation of both alleles of the RB1 gene during normal retinal development initiates the formation of a retinoblastoma (RB) tumor. To identify the mutations which inactivate RB1, 21 RB tumors isolated from 19 patients were analyzed with the polymerase chain reaction or an RNase protection assay...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Biol
主要な著者: Dunn, J M, Phillips, R A, Zhu, X, Becker, A, Gallie, B L
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363605/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2601691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.11.4596-4604.1989
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