Loading...

Mutations in the RB1 gene and their effects on transcription.

Inactivation of both alleles of the RB1 gene during normal retinal development initiates the formation of a retinoblastoma (RB) tumor. To identify the mutations which inactivate RB1, 21 RB tumors isolated from 19 patients were analyzed with the polymerase chain reaction or an RNase protection assay...

Full description

Saved in:
Bibliographic Details
Main Authors: Dunn, J M, Phillips, R A, Zhu, X, Becker, A, Gallie, B L
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC363605/
https://ncbi.nlm.nih.gov/pubmed/2601691
Tags: Add Tag
No Tags, Be the first to tag this record!