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Vpu Binds Directly to Tetherin and Displaces It from Nascent Virions
Tetherin (Bst2/CD317/HM1.24) is an interferon-induced antiviral host protein that inhibits the release of many enveloped viruses by tethering virions to the cell surface. The HIV-1 accessory protein, Vpu, antagonizes Tetherin through a variety of proposed mechanisms, including surface downregulation...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635990/ https://ncbi.nlm.nih.gov/pubmed/23633949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003299 |
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