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SIV Nef Proteins Recruit the AP-2 Complex to Antagonize Tetherin and Facilitate Virion Release

Lentiviral Nef proteins have multiple functions and are important for viral pathogenesis. Recently, Nef proteins from many simian immunodefiency viruses were shown to antagonize a cellular antiviral protein, named Tetherin, that blocks release of viral particles from the cell surface. However, the m...

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Detalhes bibliográficos
Main Authors: Zhang, Fengwen, Landford, Wilmina N., Ng, Melinda, McNatt, Matthew W., Bieniasz, Paul D., Hatziioannou, Theodora
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098198/
https://ncbi.nlm.nih.gov/pubmed/21625568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002039
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