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SIV Nef Proteins Recruit the AP-2 Complex to Antagonize Tetherin and Facilitate Virion Release

Lentiviral Nef proteins have multiple functions and are important for viral pathogenesis. Recently, Nef proteins from many simian immunodefiency viruses were shown to antagonize a cellular antiviral protein, named Tetherin, that blocks release of viral particles from the cell surface. However, the m...

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Autors principals: Zhang, Fengwen, Landford, Wilmina N., Ng, Melinda, McNatt, Matthew W., Bieniasz, Paul D., Hatziioannou, Theodora
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098198/
https://ncbi.nlm.nih.gov/pubmed/21625568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002039
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