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Tetherin inhibits HIV-1 release by directly tethering virions to cells
Tetherin is an interferon-induced protein whose expression blocks the release of HIV-1 and other enveloped viral particles. The underlying mechanism by which tetherin functions, and whether it directly or indirectly causes virion retention are unknown. Here, we elucidate the mechanism by which tethe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844890/ https://ncbi.nlm.nih.gov/pubmed/19879838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.08.039 |
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