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Structural insight into the mechanisms of enveloped virus tethering by tetherin
Tetherin/BST2 is a type-II membrane protein that inhibits the release of a range of enveloped viruses, including HIV-1. Here we report three crystal structures of human tetherin, including the full-length ectodomain, a triple cysteine mutant and an ectodomain truncation. These structures show that t...
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972963/ https://ncbi.nlm.nih.gov/pubmed/20940320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011485107 |
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