CD40 ligation reverses T cell tolerance in acute myeloid leukemia

Spontaneous antigen-specific T cell responses can be generated in hosts harboring a variety of solid malignancies, but are subverted by immune evasion mechanisms active within the tumor microenvironment. In contrast to solid tumors, the mechanisms that regulate T cell activation versus tolerance to...

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Bibliografiske detaljer
Main Authors: Zhang, Long, Chen, Xiufen, Liu, Xiao, Kline, Douglas E., Teague, Ryan M., Gajewski, Thomas F., Kline, Justin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635717/
https://ncbi.nlm.nih.gov/pubmed/23619361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63980
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