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PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
Negative regulatory mechanisms within the solid tumor microenvironment inhibit antitumor T-cell function, leading to evasion from immune attack. One inhibitory mechanism is up-regulation of programmed death-ligand 1 (PD-L1) expressed on tumor or stromal cells which binds to programmed death-1 (PD-1)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731636/ https://ncbi.nlm.nih.gov/pubmed/19417208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-206672 |
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