Llwytho...

PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model

Negative regulatory mechanisms within the solid tumor microenvironment inhibit antitumor T-cell function, leading to evasion from immune attack. One inhibitory mechanism is up-regulation of programmed death-ligand 1 (PD-L1) expressed on tumor or stromal cells which binds to programmed death-1 (PD-1)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Long, Gajewski, Thomas F., Kline, Justin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731636/
https://ncbi.nlm.nih.gov/pubmed/19417208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-206672
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