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Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

Substitution of asparagine for serine at position 17 decreased the affinity of rasH p21 for GTP 20- to 40-fold without significantly affecting its affinity for GDP. Transfection of NIH 3T3 cells with a mammalian expression vector containing the Asn-17 rasH gene and a Neor gene under the control of t...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Feig, L A, Cooper, G M
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1988
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363555/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3145408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.8.3235
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