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Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.
Substitution of asparagine for serine at position 17 decreased the affinity of rasH p21 for GTP 20- to 40-fold without significantly affecting its affinity for GDP. Transfection of NIH 3T3 cells with a mammalian expression vector containing the Asn-17 rasH gene and a Neor gene under the control of t...
Gorde:
| Argitaratua izan da: | Mol Cell Biol |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Taylor & Francis
1988
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363555/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3145408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.8.3235 |
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