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Compartmentalized Ras Proteins Transform NIH 3T3 Cells with Different Efficiencies
Ras GTPases were long thought to function exclusively from the plasma membrane (PM). However, a current model suggests that Ras proteins can compartmentalize to regulate different functions, and an oncogenic H-Ras mutant that is restricted to the endomembrane can still transform cells. In this study...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067814/ https://ncbi.nlm.nih.gov/pubmed/21189290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00137-10 |
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